Anti-ssDNA antibodies are generally not useful in the diagnosis and management of SLE. Antibodies that identify ssDNA react primarily with the purine and pyrimidine bases that are buried within the beta helix of dsDNA.
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Anti-ssDNA antibodies are generally not useful in the diagnosis and management of SLE. Antibodies that identify ssDNA react primarily with the purine and pyrimidine bases that are buried within the beta helix of dsDNA.